Genomics
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Publications

To learn more about our work and research, check out a curated list of our published articles!
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Home » Publications
  • Early Changes in Tumor-Naive Cell-Free Methylomes and Fragmentomes Predict Outcomes in Pembrolizumab-Treated Solid Tumors
    Cancer Discovery, 14(6), 1048–1063 (2024)
  • A Phase II, Open-Label, Randomized Trial of Durvalumab With Olaparib or Cediranib in Patients With Mismatch Repair—Proficient Colorectal or Pancreatic Cancer
    Clinical Colorectal Cancer, 23(3), 272-284 (2024)
  • Early Cancer Detection in Li–Fraumeni Syndrome with Cell-Free DNA.
    Cancer Discovery, 14 (1),104–119 (2024)
  • Identifying Mechanisms of Resistance by Circulating Tumor DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at Time of PARP Inhibitor Progression
    Clinical Cancer Research, 29(18), 3706–3716 (2023)
  • Transcriptomic changes in liver transplant recipients with non-alcoholic steatohepatitis indicate dysregulation of wound healing
    Frontiers in Endocrinology, 14, (2023)
  • RBFOX2 Modulates a Metastatic Signature of Alternative Splicing in Pancreatic Cancer
    Nature, 617, 147–153 (2023)
  • A polygenic two-hit hypothesis for prostate cancer
    Journal of the National Cancer Institute, 115(4), 468–472 (2023)
  • Coronavirus disease 2019 (COVID-19) outbreak on an in-patient medical unit associated with unrecognized exposures in common areas—Epidemiological and whole-genome sequencing investigation
    Infection Control & Hospital Epidemiology, 44(11), 1829 – 1833 (2023)
  • Molecular characterisation of pancreatic ductal adenocarcinoma with NTRK fusions and review of the literature
    Journal of Clinical Pathology, 76, 158-165 (2023)
  • Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
    Cancer Research Communications, 3(2), 267–280 (2023)
  • In-depth characterization of intratumoral heterogeneity in refractory B-cell non-Hodgkin lymphoma through the lens of a Research Autopsy Program
    Haematologica, 108(1), 196-206 (2023)
  • hENT1 Expression Predicts Response to Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Ductal Adenocarcinoma
    Clinical Cancer Research, 28(23), 5115–5120 (2022)
  • Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada
    Scientific Reports, 12, Article number: 10867 (2022)
  • Pancreatic cancer evolution and heterogeneity: integrating omics and clinical data
    Nature Reviews Cancer, 22, 131–142 (2022)
  • Molecular and Pathology Features of Colorectal Tumors and Patient Outcomes Are Associated with Fusobacterium nucleatum and Its Subspecies animalis
    Cancer Epidemiology, Biomarkers & Prevention, 31(1), 210–220 (2022)
  • Early signatures of breast cancer up to seven years prior to clinical diagnosis in plasma cell-free DNA methylomes
    Research Square, (2022)
  • DNA Methylation-Based Classification of Small B-Cell Lymphomas: A Proof-of-Principle Study
    The Journal of Molecular Diagnostics, 23(12), 1774-1786 (2021)
  • The telomere length landscape of prostate cancer
    Nature Communications, 12, Article number: 6893 (2021)
  • Genomic Landscape of Malignant Peripheral Nerve Sheath Tumor‒Like Melanoma
    Journal of Investigative Dermatology, 141(10), 2470-2479 (2021)
  • Antitumor immune effects of preoperative sitravatinib and nivolumab in oral cavity cancer: SNOW window-of-opportunity study
    Journal for ImmunoTherapy of Cancer, 9, (2021)
  • Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity
    Nature Communications, 12, Article number: 5137 (2021)
  • Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function
    Cells, 10(8), 2081 (2021)
  • Detection of the novel SARS-CoV-2 European lineage B.1.177 in Ontario, Canada
    Journal of Clinical Virology Plus, 1(1–2) 2021
  • Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers
    Scientific Reports, 11, Article number: 10619 (2021)
  • Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first-line platinum chemotherapy in high grade serous ovarian cancer
    Cancer Medicine, 10, 3045-3058 (2021)
  • Epigenomic, genomic, and transcriptomic landscape of schwannomatosis
    Acta Neuropathologica, 141, 101–116 (2021)
  • Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
    Nature Communications, 11, Article number: 4748 (2020)
  • Sex differences in oncogenic mutational processes
    Nature Communications, 11, Article number: 4330 (2020)

Genomics
  • Project Initiation
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    • Bring Your Own Data
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Genomics

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