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Canadian Bioinformatics Workshop: Bridging Pathology and Genomics: A Practical Workshop on NGS for Pathologists and Pathology Researchers

Toronto, ON October 21-22, 2024 The characterization of sequence variants in a patient’s tumour is key to individualized cancer care. Next-generation sequencing (NGS) is used widely to identify genetic variants in clinical oncology samples. Clinical laboratory professionals and researchers tasked with interpreting molecular results would benefit from understanding the strengths and limitations of the chemical […]

Canadian Bioinformatics Workshop: RNA-seq analysis

Toronto, ON June 17-19, 2024 High-throughput sequencing of RNA libraries (RNA-seq) has become increasingly common and has become the industry standard for transcriptome profiling. When processed appropriately, RNA-seq data has the potential to provide an exceptionally richview of the transcriptome. The CBW has developed a 3-day course providing an introduction to bulk RNA-seq data analysis […]

Early Changes in Tumor-Naive Cell-Free Methylomes and Fragmentomes Predict Outcomes in Pembrolizumab-Treated Solid Tumors

Cancer Discovery, 14(6), 1048–1063 (2024)

A Phase II, Open-Label, Randomized Trial of Durvalumab With Olaparib or Cediranib in Patients With Mismatch Repair—Proficient Colorectal or Pancreatic Cancer

Clinical Colorectal Cancer, 23(3), 272-284 (2024)

Early Cancer Detection in Li–Fraumeni Syndrome with Cell-Free DNA.

Authors Derek Wong; Ping Luo; Leslie E. Oldfield; Haifan Gong; Ledia Brunga; Ron Rabinowicz; Vallijah Subasri; Clarissa Chan; Tiana Downs; Kirsten M. Farncombe; Beatrice Luu; Maia Norman; Julia A. Sobotka; Precious Uju; Jenna Eagles; Stephanie Pedersen; Johanna Wellum; Arnavaz Danesh; Stephenie D. Prokopec; Eric Y. Stutheit-Zhao; Nadia Znassi; Lawrence E. Heisler; Richard Jovelin; Bernard Lam; […]

Identifying Mechanisms of Resistance by Circulating Tumor DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at Time of PARP Inhibitor Progression

Clinical Cancer Research, 29(18), 3706–3716 (2023)

Transcriptomic changes in liver transplant recipients with non-alcoholic steatohepatitis indicate dysregulation of wound healing

Frontiers in Endocrinology, 14, (2023)

RBFOX2 Modulates a Metastatic Signature of Alternative Splicing in Pancreatic Cancer

Nature, 617, 147–153 (2023)

Coronavirus disease 2019 (COVID-19) outbreak on an in-patient medical unit associated with unrecognized exposures in common areas—Epidemiological and whole-genome sequencing investigation

Infection Control & Hospital Epidemiology, 44(11), 1829 – 1833 (2023)

Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma

Cancer Research Communications, 3(2), 267–280 (2023)