Clinical Reporting Services
CAP, ACD and ISO 15189-compliant, high-quality sequencing and analysis services available for clinical diagnostics. These services utilize our Requisition System and generate clinical reports, which are completed by certified geneticists. Prices per case are listed below and are valid as of March 2022.
WGTS and WGS assay turnaround time is 45 calendar days; Targeted Sequencing assay turnaround time is 21 calendar days.
| Assay | Details | Cost (CAD) |
|---|---|---|
| Whole Genome and Transcriptome Sequencing (WGTS) | 80X Tumour, 30X Normal | $7840 |
| Whole Genome and Transcriptome Sequencing (WGTS) | 40X Tumour, 30X Normal | $5540 |
| Whole Genome Sequencing (WGS) | 80X Tumour, 30X Normal | $7130 |
| Whole Genome Sequencing (WGS) | 40X Tumour, 30X Normal | $4800 |
| Targeted Sequencing – CHARM Panel | Tumour & buffy coat | $1152 |
| Targeted Sequencing – CHARM Panel | cfDNA & buffy coat | $1152 |
| Targeted Sequencing – CHARM Panel | Tumour only, follow-up | $825 |
| Targeted Sequencing – CHARM Panel | cfDNA only, follow-up | $825 |
| Targeted Sequencing – REVOLVE Panel | Tumour & buffy coat | $1435 |
| Targeted Sequencing – REVOLVE Panel | cfDNA & buffy coat | $1435 |
| Targeted Sequencing – REVOLVE Panel | Tumour only, follow-up | $1119 |
| Targeted Sequencing – REVOLVE Panel | cfDNA only, follow-up | $1119 |
Clinical Resources
Sequencing Services
From tissue extraction to targeted, whole genome/exome/transcriptome, or customized sequencing, we can help at any stage of your genomics research, even if you are working with low input and/or low quality biospecimens. We utilize a fleet of Illumina instruments, including the MiSeq, NextSeq 550 and NovaSeq 6000, as well as the Oxford Nanopore MinION and PromethION. Prices per sample are listed below and are valid as of March 2022.
| Service | Cost (CAD) |
|---|---|
| Dual DNA/RNA Extraction from FFPE | $70 |
| DNA Extraction from Tissue/Blood/Buffy Coat | $50 |
| cfDNA Extraction | $55 |
| RNA Extraction from Fresh Frozen Tissue | $55 |
| HMW DNA Extraction | $100 |
| Whole Genome Sequencing (WGS) – 30X, 40X, 50X, 80X | $1570, $2030, $2480, $3860 |
| Whole Transcriptome Sequencing (WTS) – TruSeq 50M, 100M PE reads (cluster) | $590, $770 |
| Whole Exome Sequencing (WES) – IDT 50X, 100X, 200X | $490, $650, $970 |
| cfMeDIP – 20M, 40M, 80M, 120M PE reads | $500, $570, $700, $830 |
| Targeted Sequencing – onboard a new panel or use an existing one | please request quotation |
| Single Molecule Molecular Inversion Probes (smMIP) | please request quotation |
| Oxford Nanopore – DNA, RNA, or Long Read Epigenome | please request quotation |
| Library Sequencing – sequence on MiSeq, NextSeq or NovaSeq | please request quotation |
Bioinformatics Services
The Genome Sequence Informatics group develops and uses a variety of automated and semi-automated analysis workflows to fulfill every project’s unique needs, whether for clinical trials or research projects.
Most of our analysis is packaged together with in-house sequencing packages and will not be quoted separately, unless additional analysis is requested. The values below are approximate. They are valid as of October 2022.
| Assay | Package level | Cost (CAD) |
|---|---|---|
| Reads only (FASTQ) | FASTQ only | $474/lane |
| Whole genome | basic alignment | $20/library/run |
| Whole genome | alignment, merged and call-ready | $30/sample |
| Whole genome | standard analysis | $40/sample |
| Exome | basic alignment | $10/library/run |
| Exome | alignment, merged and call-ready | $15/sample |
| Exome | standard analysis, T/N pair | $25/pair |
| Exome | standard analysis, tumour only | $20/sample |
| Targeted/panel | basic alignment | $2/library/run |
| Targeted/panel | standard analysis | $5/sample |
| Whole transcriptome | basic alignment | $10/library/run |
| Whole transcriptome | standard analysis | $25/sample |
| Nanopore | Please request quotation | |
| Shallow whole genome | standard analysis | $7/sample |
For more information on validated pipelines, standard packages, and other analysis offerings, please see the Genome Sequence Informatics page.
Request a quoteAnalysis Resources
- Validated pipelines for clinical assays
- Standard analysis packages
- Djerba: Generating Clinical Genome Interpretation Reports for Cancer