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Liquid Biopsy – OMPRN

Learn about a relatively new medical testing technique called liquid biopsy, courtesy of Ontario Molecular Pathology Research Network.

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Sample Submission Instructions

Prior to submitting your samples to OICR, please make sure to complete the Project Initiation Form. Once the project has been approved and the project code has been assigned, the user will be referred to our Tissue Portal team for sample submission. At OICR Genomics we work with fresh frozen (FF) tissue, formalin-fixed paraffin embedded […]

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Terms and Conditions of Service

Revision – July 2023. To initiate a project with OICR genomics (“we”,”us”) our staff will work with you to to define the objectives and deliverables through our Project Initiation Form (“PIF”). The information in this PIF will be used to create a project estimate (“Estimate”). Upon acceptance of the Estimate, the OICR Purchase Order Standard […]

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Whole Transcriptome Library Preparation Protocol

Based on Version 7.1 of TM-026 WTS Library Preparation – Illumina TruSeq. Purpose To define the Whole Transcriptome Sequencing (WTS) library preparation procedure, using the Illumina TruSeq Stranded Total RNA Library Prep Gold kit. Scope Following extraction and initial Quality Control (QC), samples in the WTS workflow must undergo library preparation. A library consists of […]

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Whole Genome Library Preparation Protocol

Based on Version 8.1 of TM-025 WGS Library Preparation – KAPA. Purpose To define the Whole Genome Sequencing (WGS) library preparation procedure, using the KAPA Hyper Prep Kit. Scope Following extraction and initial Quality Control (QC), samples in the WGS workflow must undergo library preparation. A library consists of DNA fragments with ligated adapters and […]

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Reading Clinical Reports

Our clinical reports are generated through Djerba, which houses our 47 clinical workflows. The report is generated for individual patients based on the results of sequencing and are accredited for clinical use. The document contains the assay results, interpretation of said results, and any treatment that might be recommended based on the results. Please find […]

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Leadership and Staff

Leadership Trevor Pugh, PhD, FACMG Program Director and Principal Investigator, Genomics Dr. Trevor Pugh, PhD, FACMG is a cancer genomics researcher, board-certified molecular geneticist, and holder of the Canada Research Chair in Translational Genomics. He is appointed as Professor in the University of Toronto Department of Medical Biophysics, Senior Scientist at the Princess Margaret Cancer […]

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Canadian Bioinformatics Workshop: Bridging Pathology and Genomics: A Practical Workshop on NGS for Pathologists and Pathology Researchers

Toronto, ON October 21-22, 2024 The characterization of sequence variants in a patient’s tumour is key to individualized cancer care. Next-generation sequencing (NGS) is used widely to identify genetic variants in clinical oncology samples. Clinical laboratory professionals and researchers tasked with interpreting molecular results would benefit from understanding the strengths and limitations of the chemical […]